2017 | Insights into the Structural Requirements of Potent Brassinosteroids as Vegetable Growth Promoters Using Second-Internode Elongation as Biological Activity: CoMFA and CoMSIA Studies. | Luis Espinoza y Jaime Mella | Artículo | International Journal of Molecular Sciences. 18(12):2734. | link |
2017 | Aplicaciones clínicas de células madres derivadas de tejido adiposo y aspectos relacionados con buenas prácticas de manufactura.
| Caroline Weinstein | Artículo | Anales de la Real Academia Nacional de Farmacia. 83:329-402 | link |
2018 | Mass Median Plume Angle: A novel approach to characterize plume geometry in solution based pMDIs | Daniel Moraga | Artículo | International Journal of Pharmaceutics 543; (1–2):376-385 | link |
2018 | Effect of Inhalation Flow Rate on Mass-Based Plume Geometry of Commercially Available Suspension pMDIs | Daniel Moraga | Artículo | The AAPS journal 20:84 | link |
2018 | A modified USP induction port to characterize nasal spray plume geometry and predict turbinate deposition under flow | Daniel Moraga | Artículo | International Journal of Pharmaceutics 548(1):305-313 | link |
2018 | Development, characterization, and in vitro testing of co-delivered antimicrobial dry powder formulation for the treatment of Pseudomonas aeruginosa biofilms | Daniel Moraga y Tania Bahamóndez | Artículo | Journal of Pharmaceutical Sciences 107(8):2172-2178 | link |
2018 | Inflammatory and Pro-resolving Lipids in Trypanosomatid Infections: A Key to Understanding Parasite Control | Carolina Campos | Artículo | Frontiers in Microbiology 9:1961 | link |
2018 | Structure-Activity Relationships Based on 3D-QSAR CoMFA/CoMSIA and Design of Aryloxypropanol-Amine Agonists with Selectivity for the Human β3-Adrenergic Receptor and Anti-Obesity and Anti-Diabetic Profiles | Jaime Mella | Artículo | Molecules 23(5):1191 | link |
2018 | Synthesis of chalcones with antiproliferative activity on the SH-SY5Y neuroblastoma cell line quantitative structure
| Caroline Weinstein, Jaime Mella y Mauricio Cuellar | Artículo | Medicinal Chemistry Research 27, 2414–2425 | link |
2018 | Antifeedant effect of polygodial and drimenol derivatives against Spodoptera frugiperda and derivatives against Spodoptera frugiperda and Epilachna paenulata and quantitative structure-activity analysis | Mauricio Cuellar | Artículo | Pest Management Science 74(7):1623-1629 | link |
2018 | (-)-Shikimic Acid as a Chiral Building Block for the Synthesis of New Cytotoxic 6-Aza-Analogues of angucyclinones | Natalia Quiñones, Luis Espinoza y Mauricio Cuellar | Artículo | Molecules 23(6):1422 | link |
2019 | Three-Dimensional Quantitative Structure-Activity Relationships (3D-QSAR) on a Series of Piperazine-Carboxamides Fatty Acid Amide Hydrolase (FAAH) Inhibitors as a Useful Tool for the Design of New Cannabinoid Ligands | Jaime Mella | Artículo | International Journal of Molecular Sciences. 20(10):2510. | link |
2019 | Antiproliferative and proapoptotic activities of aza-annulated naphthoquinone analogs | Jaime Mella | Artículo | Toxicology in Vitro 54:375-390 | link |
2019 | Design, synthesis, antifungal activity, and structure–activity relationship studies of chalcones and hybrid dihydrochromane–chalcones | Luis Espinoza, Jaime Mella y Mauricio Cuellar | Artículo | Molecular Diversity 24:603–615 | link |
2019 | Design, Synthesis and Docking Calculations of Prenylated Chalcones as Selective Monoamine Oxidase B Inhibitors with Antioxidant Activity. | Mauricio Cuellar | Artículo | Chemistry Select 4(26):7698-7703 | link |
2019 | Lack of association between the IL6R GENE ASP358ALA Variant (RS2228145), IL-6 plasma levels and treatment resistance in chilean schizophrenic patients treated with clozapine | Carolina Campos | Artículo | Schizophrenia Research and Treatment 5601249 | link |
2019 | Epanorin, a lichen secondary metabolite, inhibits proliferation of MCF-7 breast cancer cells | Natalia Quiñones y Caroline Weinstein | Artículo | Biological Research 52:55 | link |
2019 | Impacto del Polimorfismo Genético de CYP2D6 en la Enfermedad de Parkinson
| Caroline Weinstein | Artículo | Revista de Farmacologia de Chile 12(1):21-33 | link |
2019 | Antigrowth activity and induction of apoptosis in human melanoma cells by Drymis winteri forst extract and its active components. | Mauricio Cuellar | Artículo | Chemico-Biological Interactions 305:79-85 | link |
2019 | La Farmacopea Chilena versión 2016 y su aporte a la medicina tradicional | Marcela Escobar y Caroline Weinstein | Artículo | Cuadernos Médico Sociales 60(3) | link |
2019 | Overview of the delivery technologies for inhalation aerosols. Inhalation Aerosols: Physical and Biological Basis for Therapy | Daniel Moraga | Capítulo de libro | Inhalation aerosols | link |
2019 | A critical perspective on future developments based on the knowledge we have now | Tania Bahamóndez | Capítulo de libro | Inhalation aerosols | link |
2020 | In vivo efficacy of a dry powder formulation of ciprofloxacin-copper complex in a chronic lung infection model of bioluminescent Pseudomonas aeruginosa | Tania Bahamóndez y Daniel Moraga | Artículo | European Journal of Pharmaceutics and Biopharmaceutics 152:210-217 | link |
2020 | In vitro Notch-mediated adjuvant immunogenic potency is induced by combining QS-21 and MPL in a co-culture model of PBMC and HUVEC cells | Carolina Campos | Artículo | Toxicology in Vitro 68:104947 | link |
2020 | Synthesis, Docking, 3-D-Qsar, and Biological Assays of Novel Indole Derivatives Targeting Serotonin Transporter, Dopamine D2 Receptor, and Mao-A Enzyme: In the Pursuit for Potential Multitarget Directed Ligands | Jaime Mella | Artículo | Molecules 25(20):4614 | link |
2020 | Notch receptor expression in Trypanosoma cruzi-infected human umbilical vein endothelial cells treated with benznidazole or simvastatin revealed by microarray analysis. | Jaime Mella | Artículo | Cell Biology International 44(5):1112-1123 | link |
2020 | Synthesis, in vitro evaluation and molecular docking of a new class of indolylpropyl benzamidopiperazines as dual AChE and SERT ligands for Alzheimer’s disease
| Jaime Mella | Artículo | European Journal of Medicinal Chemistry 198:112368 | link |
2020 | DARK Classics in Chemical Neuroscience: Heroin and Desomorphine | Jaime Mella | Artículo | ACS Chemical Neuroscience 11(23):3905–3927 | link
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2020 | Autorización de uso de emergencia primera vacuna RNA para COVID-19 en Chile | Caroline Weinstein | Editorial | Revista Médica de Chile 148(12) | link |
2021 | Antiproliferative Rapeseed Defatted Meal Protein and Their Hydrolysates on MCF-7 Breast Cancer Cells and Human Fibroblasts. | Caroline Weinstein | Artículo | Foods 10(2):309 | link |
2021 | Restraint of Human Skin Fibroblast Motility, Migration, and Cell Surface Actin Dynamics, by Pannexin 1 and P2X7 Receptor Signaling | Caroline Weinstein | Artículo | International Journal of Molecular Sciences. 22(3):1069 | link |
2021 | Natural isoflavonoids in invasive cancer therapy: From bench to bedside | Caroline Weinstein | Artículo | Phytotherapy Research 35(8):4092-4110 | link |
2021 | Avances y desafíos en las vacunas el para control de la pandemia por COVID-19 | Caroline Weinstein | Editorial | ARS Médica Revista de Ciencias Médicas 46(2) | link |
2021 | Alfabetización estadística y comunicación de riesgo para la vacunación contra la COVID-19:una revisión de alcance | Caroline Weinstein | Artículo | Pan American Journal of Public Health 45 | link |
2021 | El caso de aducanumab ¿Más esperanza que ciencia? | Caroline Weinstein | Artículo | ARS Médica Revista de Ciencias Médicas 46(3) | link |
2021 | Inhibition of Caco-2 and MCF-7 cancer cells using chalcones: synthesis, biological evaluation and computational study | Caroline Weinstein | Artículo | Natural Product Research 36(17): 4404-4410 | link |
2021 | The science behind the development of anti-SARS-CoV-2 vaccines | Caroline Weinstein | Artículo | Revista de Farmacologia de Chile 14(1):6-14 | link |
2021 | Differences in volatile emissions between healthy and gall-induced branches of Haplopappus foliosus (Asteraceae) | Waleska Vera | Artículo | Biochemical Systematics and Ecology 98: 104309 | link |
2021 | Innovating on inhaled bioequivalence: A critical analysis of the current limitations, potential solutions and stakeholders of the process | Tania Bahamóndez y Daniel Moraga | Artículo | Pharmaceutics 13(7):1051 | link |
2021 | Nuevas perspectivas para el tratamiento de la infección por Helicobacter pylori | Tania Bahamóndez | Artículo | ARS Médica Revista de Ciencias Médicas 46(2), 60-69 | link |
2021 | Novel N-Arylsulfonylindoles Targeted as Ligands of the 5-HT6 Receptor. Insights on the Influence of C-5 Substitution on Ligand Affinity. | Jaime Mella | Artículo | Pharmaceuticals 14(6):528. | link |
2021 | Combined 3D-QSAR and docking analysis for the design and synthesis of chalcones as potent and selective monoamine oxidase B inhibitors | Jaime Mella y Mauricio Cuellar | Artículo | Bioorganic Chemistry 108: 104689 | link |
2022 | QSAR-driven synthesis of antiproliferative chalcones against SH-SY5Y cancer cells: Design, biological evaluation, and redesign | Caroline Weinstein, Jaime Mella y Mauricio Cuellar | Artículo | Arch Pharm 355(7):2200042 | link |
2022 | Involvement of Inflammation and Its Resolution in Disease and Therapeutics | Caroline Weinstein y Carolina Campos | Artículo | International Journal of Molecular Sciences 23(18):10719. | link |
2022 | Formulation of water soluble Buddleja globosa Hope extracts and characterization of their antimicrobial properties against Pseudomonas aeruginosa | Daniel Moraga y Tania Bahamóndez | Artículo | Frontiers in Pharmacology 13: 921511 | link |
2022 | Cytotoxic Effects on Breast Cancer Cell Lines of Chalcones Derived from a Natural Precursor and Their Molecular Docking Analysis | Mauricio Cuellar | Artículo | Molecules 27(14):4387 | link |
2022 | New Amino Naphthoquinone Derivatives as Anti-Trypanosoma cruzi Agents Targeting Trypanothione Reductase | Mauricio Cuellar | Artículo | Pharmaceutics 14(6):1121 | link |
2022 | In Silico Studies and Inhibitory Activity towards Bcr-Abl, BTK and FLT3-ITD of New 2,6,9-Trisubstituted Purine Derivatives as Potential Agents for the Treatment of Leukaemia. | Jaime Mella | Artículo | Pharmaceutics 14(6):1294 | link |
2023 | The Antiproliferative Activity of a Mixture of Peptide and Oligosaccharide Extracts Obtained from Defatted Rapeseed Meal on Breast Cancer Cells and Human Fibroblasts | Caroline Weinstein | Artículo | Foods 12(2):253 | link |
2023 | Effect of statins on inflammation and cardiac function in patients with chronic Chagas disease: A protocol for pathophysiological studies in a multicenter, placebo-controlled, proof-of-concept phase II trial | Carolina Campos | Artículo | PLoS ONE 18(1): e0280335 | link |
2023 | Cancer and brassinosteroids: Mechanisms of action, SAR and future perspectives | Luis Espinoza y Jaime Mella | Artículo | Steroids 190, 109153 | link |
2023 | In silico approaches to develop new phenyl-pyrimidines as glycogen synthase kinase 3 (GSK-3) inhibitors with halogen-bonding capabilities: 3D-QSAR CoMFA/CoMSIA, molecular docking and molecular dynamics studies | Jaime Mella | Artículo | Journal of Biomolecular Structure and Dynamics | link |
2023 | Design of benzimidazoles, benzoxazoles, benzothiazoles and thiazolopyridines as leukotriene A4 hydrolase inhibitors through 3D-QSAR, docking and molecular dynamics | Jaime Mella | Artículo | Journal of the Serbian Chemical Society 88(1):25-39 | link |
2023 | Cytotoxic Activity, Topoisomerase I Inhibition and In Silico Studies of New Sesquiterpene-aryl Ester Derivatives of (-) Drimenol | Jaime Mella, Luis Espinoza, Waleska Vera y Mauricio Cuellar | Articulo | Molecules 28(9):3959 | link |
2023 | Infection of perennial ryegrass (Lolium perenne) by an endophyte fungus (Neotyphodium lolii) decreases the abundance and diversity of predators and parasitoids | Waleska Vera | Artículo | Revista Brasileira de Entomologia 64(3) | link |
2023 | The forgotten material: Highly dispersible and swellable gelatin-based microspheres for pulmonary drug delivery of cromolyn sodium and ipratropium bromide
| Daniel Moraga, Tania Bahamóndez y Carolina Campos | Artículo | International Journal of Pharmaceutics 644:123331 | link |
2023 | Organoides de origen humano como modelo fisiopatológico de evaluación terapéutica de fármacos en COVID-19 | Caroline Weinstein, Daniel Moraga, Tania Bahamóndez y Carolina Campos | Artículo | ARS Medica Revista de Ciencias Medicas 48(3):36-47 | link |
2023 | Effect of statins on inflammation and cardiac function in patients with chronic Chagas disease: A protocol for pathophysiological studies in a multicenter, placebo-controlled, proof-of-concept phase II trial | Carolina Campos | Artículo | PLoS One, 18(1), e0280335 | link |
2024 | New Brassinosteroid Analogs with 23,24-Dinorcholan Side Chain, and Benzoate Function at C-22: Synthesis, Assessment of Bioactivity on Plant Growth, and Molecular Docking Study | Luis Espinoza y Mauricio Cuellar | Artículo | International Journal of Molecular Sciences 25(1), 419 | link |
2024 | Feeding Performance of Argentine Stem Weevil Is Reduced by Peramine from Perennial Ryegrass Infected with Endophyte Fungus. | Waleska Vera | Artículo | Insects, 15(6), 410. | link |
2024 | Ca2+ signals in human umbilical endothelial cells derived from pregnancy with fetal growth restriction associated with hypertensive disorder | Tania Bahamóndez | Artículo | Biomedical Reports 20(5):76 | link |
2024 | Essential Pharmaceutics | Tania Bahamóndez y Daniel Moraga | Libro | Springer Link | link |
2024 | Comparison of the removal of Ciprofloxacin and Moxifloxacin between adsorption–photolysis and adsorption–photocataysis processes | Juan Ojeda | Artículo | International Journal of Environmental Science and Technology | link |
2024 | Effect of Cannabis sativa L extracts, phytocannabinoids and their acetylated derivates on the SHSY-5Y neuroblastoma cells´ viability and caspases 3/7 activation | Luis Espinoza, Caroline Weinstein y Mauricio Cuellar | Artículo | Biological Research 57(33) | link |
2024 | Assessment of the Activity of Nitroisoxazole Derivatives against Trypanosoma cruzi | Michel Lapier | Artículo | Molecules, 29(12), 2762. | link |
2024 | Antimicrobial Activity of Drimanic Sesquiterpene Compounds from Drimys winteri against Multiresistant Microorganisms. | Luis Espinoza y Mauricio Cuellar | Artículo | Molecules, 29(12), 2844 | link |
2024 | Novel Brassinosteroid Analogues with 3,6 Dioxo Function, 24-Nor-22(S)-Hydroxy Side Chain and p-Substituted Benzoate Function at C-23—Synthesis and Evaluation of Plant Growth Effects. | Mauricio Cuellar y Luis Espinoza | Artículo | International Journal of Molecular Sciences, 25(14), 7515 | link |
2024 | Kalanchoe pinnata (Lam.) Pers. Leaf ethanolic extracts exerts selective anticancer activity through ROS-induced apoptotic cell death in human cancer cell lines | Waleska Vera y Marcela Escobar | Artículo | BMC Complementary Medicine and Therapies, 24(1), 269 | link |
2024 | Exudate and Propolis from Escallonia pulverulenta: Phytochemical Characterization and Antibacterial Activity | Waleska Vera | Artículo | Plants 2024, 13(14), 1971 | link |
2024 | NLRP3 inflammasome as a therapeutic target in cardiovascular diseases: An update of preclinical and clinical evidence | Carolina Campos | Artículo | Journal of International Crisis and Risk Communication Research 7(6), 1361–1377 | link |
2024 | 2D/3D-QSAR Model Development Based on a Quinoline Pharmacophoric Core for the Inhibition of Plasmodium falciparum: An In Silico Approach with Experimental Validation. | Jaime Mella | Artículo | Pharmaceutics 2024, 17(5):606 | link |
2024 | Arylamines QSAR-Based Design and Molecular Dynamics of New Phenylthiophene and Benzimidazole Derivatives with Affinity for the C111, Y268, and H73 Sites of SARS-CoV-2 PLpro Enzyme | Jaime Mella | Artículo | Pharmaceuticals 2024, 17(5), 606 | link |
2024 | Phytoconstituents, Antioxidant Activity and Cytotoxicity of Puya chilensis Mol. Extracts in Colon Cell Lines. | Waleska Vera | Artículo | Plants 2024, 13(21), 2989 | link |
2024 | Repellents used against Aedes aegypti bites: synthetic and natural origin | Caroline Weinstein y Natalia Quiñones | Artículo | Frontiers in Insect Science 2024, 4, 1510857 | link |